Science Rocks features AbbVie scientists who share interesting research in their field and why it matters. In this month's feature, Cheri Enders, Ph.D., ARF, senior director of clinical pharmacology and pharmacometrics, AbbVie, shares an article about Evatar, a model of a female reproductive system that simulates a menstrual cycle and pregnancy hormones.
The coolest thing in science I’ve recently read is the application of “organs-on-chips” to the female reproductive system. The model, called Evatar, can replicate a woman’s menstrual cycle by linking five organ chips together -- an ovary, a fallopian tube, a uterus, a cervix and a liver.
This is first I’ve read about multiple organs being connected to form a nearly complete system and it’s worth noting here that the human reproductive system is extremely complex. Multiple hormones fluctuate at different times throughout a menstrual cycle to coordinate the development, maturation and release of an egg. This egg needs to be released at the right time for the uterus to accept it for implantation.