Seeking a way to treat psoriasis at its source
“Let me remind you where we stood with psoriasis when I first started my work in dermatology,” said Kristian Reich, a dermatologist and professor at the Dermatologikum in Hamburg, Germany. “Patients were spending three or four weeks in the hospital, two or three times a year. What could we offer them?”
Just 20 years ago, Reich didn’t have a good solution for his patients battling psoriasis. The majority of patients didn’t respond to the available treatment options. It was clear that these treatments weren’t enough – and they weren’t addressing the disease at its source.
Scientists and researchers knew that psoriasis was more than just a skin condition. The problem came from a faulty immune system that sent the wrong signals and caused skin cells to grow too rapidly.
But their understanding of how that breakdown in communication happened wasn’t perfectly clear. It was like opening the hood of a car, seeing the machinery inside, but not knowing exactly how it all connected.
They needed an instruction manual to help them explore the problem and fix the broken part.